Homeopathy, Herbs And Hypnosis
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Table 1. Common Homeopathic Remedies And Their Uses |
The sale of herbal medicines in the United States is one of the ten fastest growing industries. It is estimated that over 60 million adults used herbs for a medical condition in 1996. The average spent per person is $54 annually, with many people spending much more. The total estimated retail sales exceeded $3.42 million in 1996 and $441.5 million in 1997 (Figure 1). There was an estimated 78% increase in the use of herbs over this one year period. Media coverage of herbal medicines is extensive.
Figure 1. Herb Supplement Sales First 8 Months Of 1999 |
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Numerous factors contribute to this increased use of plant-derived medicines for self-treatment. Although the tremendous benefits of technology that produce dramatic effects (increasingly technical surgeries and procedures), the dangers and indiscriminate use of chemicals (preservatives, coloring agents, drugs, chemical pollution) is straining the adaptability of our complex bodies and the environment. There appears to be a growing distrust of technological medicine which has given rise to a `back to nature' movement.
Science is a double-edged sword and its enormous influence means that we must begin to realize and address the long-term consequences of our technology. Yet, both technology and nature must be combined wisely. The history of herbal medicines is as old as the history of healing itself. Only in the past fifty years, with the increase in synthetic drug manufacture and the medical promise of a drug to cure every ailment, has the use of botanicals as medicines taken a back seat to prescription, manufactured pharmaceuticals. Reasons for this are multiple. There is no dedicated support of the herbal industry by the Federal Government; the cost of bringing a new drug to market is between $140 and $500 million. With natural substances being non-patentable, pharmaceutical companies are loathe to spend the necessary research money to provide adequate research because the development money spent is non-recoverable.
In the European Commonwealth, there is less of a dichotomy between naturally-derived botanical medicines and synthetic pharmaceuticals, leading to more research, longer history of use, and stricter quality control. In phytomedicine, pathological understanding of illness is similar to western allopathic pathology, however medical herbalists view illness within the context of the healing capacity of the whole person and then chose herbs that support the specific organ systems under stress.12 Most western-trained herbalists believe that the body is a self-healing organism and that herbs should be chosen to support wellness, not simply to relieve symptoms or treat diseases. The main uses for herbs in the United States are shown in Figure 2.
Figure 2. Consumers' Use Of Herbal Remedies |
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For the past forty years, researchers have been trying to isolate the "active" constituent of a plant. As a result, the exact mechanism of action for a number of plants has been elucidated and the understanding of phytomedicines expanded. With the ability to standardize herbs that is, to accurately measure the exact percent of active constituents within an herbal product a new range of herbal medicines are now available to the public. Many practitioners feel more confident recommending a product if they know the exact amount of the active principle and the number of milligrams that should be prescribed daily.
Most plants, however, contain hundreds of constituents that may be acting in concert, not individually, to create the physiologic effect. Clinical trials that study the whole plant's activity must be designed. This requires a shift of thinking in western allopathic research a movement away from reductionism looking at herbs as complete products in which the whole is greater than the sum of its parts.
Additional evidence of widespread consumer interest in herbs and other natural products, now legally classified as "dietary supplements" in the United States, can be found in the estimated two million letters, faxes and phone calls by Americans to members of Congress during 1993 and 1994 in support of legislation that would protect and increase access to the products and information on their responsible use. The Dietary Supplement Health and Education Act (DSHEA) of 1994 created a new legal definition for dietary supplements: vitamins, minerals, herbs or other botanicals, amino acids, and other dietary substance for use by man to supplement the diet by increasing total dietary intake, including a concentrate, metabolite, constituent, extract, or combination of these ingredients (103rd Congress, 1994). A limited amount of information regarding an herb's physiologic effects can be conveyed on a product label, however therapeutic or drug claims are prohibited. That is, DSHEA allows for `statements of nutritional support' or so called `structure and function claims.'
Because of the high level of professional interest in herbs and phytomedicines in Germany, there is a considerable amount of scientific research conducted. Herbal medicines in Germany have been protected beginning with the Imperial Decree of 1901 that permitted the trade of many botanical drugs outside pharmacies. Germany's Second Medicines Act (Arzneimittelgesetz) of 1976 required the entire range of medicines in the pharmaceutical market (including conventional drugs, medicinal plants and phytomedicines) to be reviewed by a scientific committee every three years. In 1978, the Minister of Health established a series of commissions to review various categories of drugs, including an expert committee of herbal drugs and preparations from medicinal plants, Commission E. These committees were situated at the Bundesgesundheitsamt, the Federal Health Agency. This Commission E was composed of 24 members (physicians, pharmacists, non-medical practitioners, pharmacologists, toxicologists, biostatisticians, and representatives of the pharmaceutical industry). The scientists and physicians in this committee had authored over 1,000 publications. The report of this Commission E, "Therapeutic Guide to Herbal Medicines", has become one of the most complete reference works in herbal medicine in the world and was recently translated in to English.13
Some of the most commonly used herbs and their pharmacologic properties are listed below.
St. John's Wort: St. John's Wort (Hypericum perforatum) has received a great deal of attention since a story on its use appeared in the media. A meta-analysis of 23 clinical trials conducted on more than 1757 outpatients was published in the British Medical Journal in 1996 showing that the extract was more effective than placebo and equally as effective as standard synthetic antidepressants.14 Although initially classified as a monoamine oxidase inhibitor, later studies suggest that its effect may be due to serotonin reuptake inhibition.15 Even more recent studies suggest that hypericin does not cross the blood-brain barrier and that its effects are due to regulation of cytokines, specifically supression of interleukin-6.16 Hypericum also possesses antiretroviral activity both in vivo and in vitro. Both hypericin and pseudohypericin interfere with the development of viral components and directly inactive mature retroviruses.17 The usual adult dose is 300 mg three times daily, with products standardized to contain 0.3% hypericin. Pediatric dosage for children 6 to 12 is 250 mg daily. Gastrointestinal side effects may be experienced. Photosensitivity in light-skinned patients is theoretically possible but has never been reported in a human taking the herb.
Kava Kava: Kava root (Piper methysticum) is found throughout the South Pacific Islands where it has been used as a slightly intoxicating, non-alcoholic beverage for thousands of years. Several studies have demonstrated kava's effectiveness in alleviating stress and anxiety. It has also been used as a muscle relaxant and analgesic. The muscle relaxant effects are thought to be of supraspinal origin18 and the analgesic effect is not thought to operate through opiate pathways because the effect is not reversed by naloxone.19 Kava has been demonstrated to increase deep sleep without affecting REM sleep.18 Kava is a viable option in the treatment of anxiety and muscle tension before turning to the benzodiazepines and tricyclic antidepressants. Sedation is not seen in therapeutic doses recommended. There are minimal side effects weight loss and a reversible skin condition known as kava dermopathy have been reported in long term users taking very high doses.20 The usual dose of a standardized extract is 200 mg three times daily. Caution should be used when used with other psychotropic or sedative medications.
Echinacea: Echinacea (Echinacea spp. [usually purpurea]) is indigenous to North America and is exported to Europe for medicinal uses. It is used as a stimulant to the immune system. Echinacea's action on the immune system is non-specific and works primarily through cell-mediated actions - increasing activity among macrophages and lymphocytes, and increasing the number of circulating granulocytes.21 The polysaccharides found in echinacea stimulate the secretion of tumor necrosis factor, interferon, and interleukin-1.22 The arabinogalactans found within the roots have distinct antiviral properties. Echinacoside has bacteriostatic properties, while echinacin B promotes tissue granulation.23 Echinacea is a suitable herb for cold and flu-like symptoms. Patients often pressure physicians to prescribe something for obvious viral infections and antibiotics are often requested. Echinacea is an appropriate recommendation. A meta-analysis of six double-blind, placebo-controlled and randomized studies show an improvement in symptoms and decreased length of upper respiratory illness when echinacea is given. It has also been shown to be of benefit in the prophylaxis of upper respiratory infections.24 Echinacea has also been used topically to promote the healing of wounds. There are few side effects. The recommended dose of standardized extract is 900 mg two to four times daily. It can be used in children and adults.
Ginkgo: Ginkgo biloba extracts standardized to contain 24% ginkgo flavonglycosides, are among the most well-studied plant-based medicines. More than 40 double-blind studies have shown it to be effective in cerebral vascular insufficiency. The leaves have been studied for a wide number of indications including dementia, poor memory, difficulties with concentration, cerebral insufficiency syndromes (including dizziness, headache, and tenets), intermittent claudication, Raynaud's Syndrome, and asthma. Ginkgo is a potent inhibitor of platelet activating factor (PAF) which helps reduce platelet aggregation and plays a role in inhibiting bronchoconstriction,25 preventing lipid peroxidation,25 inhibiting catecholamine O-methyl transferase and stimulating synthesis of serotonin receptors. It prolongs the half-life of endothelium-derived relaxing factor resulting in dilation of the arterial bed and improved peripheral circulation. It has been shown to increase pain- free walking distance in patients suffering from intermittent claudication.26 Other studies have shown effectiveness in treating vertigo, macular degeneration, Alzheimers Disease, tenets, cochlear deafness, diabetic retinopathy, impotence, premenstrual syndrome and idiopathic cyclic edema, allergies, and depression. The standard dose is 40-80 mg three times a day. It is extremely safe and side-effects are uncommon. In 44 double-blind studies involving 9,772 patients taking GBE, the number of side effects reported was extremely small. The most common was GI discomfort and this occurred only in 21 cases, followed by headache (7 cases) and dizziness (6 cases).
Saw Palmetto: Saw palmetto (Serenoa repens) is a small palm tree native to West Indes and the Atlantic Coast of North America from South Carolina to Florida. The fat soluble extract of the berries inhibits the conversion of testosterone to dihydrotestosterone (DHT) and has been reported to have antiandrogen and estrogenic effects. In one of the larger studies involving 110 patients with BPH, impressive clinical results were reported: nocturia decreased by 45%, flow rate (ml/s) increased by over 50% and post micturition residual (ml) decreased by 42% in the group receiving saw palmetto extract while the placebo group showed no significant improvement.27 Direct comparisons with finasteride (Proscar) report increased efficacy, lower side effects, and significantly reduced cost of treatment with saw palmetto. While finasterde typically takes up to a year to produce significant benefit, most patients on saw palmetto extract achieve some symptom relief within the first 30 days. A recently reported study has now evaluated the long-term efficacy of saw palmetto. This three year, multi-center open label study evaluated 160 mg of a standardized extract in 435 men (aged 41-89 years) with stage I or II BPH. By the end of the study 120 patients had withdrawn: 12 from lack of efficacy, 41 due to need of surgery, 41 lost to follow-up, and 8 from adverse reactions. In the remaining 315, the following were reported:
Other common herbs in use in the United States, their common actions, and recommended dosages are seen in Table 2.
Table 2. Other Common Herbs And Their Uses |
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There is no organization or governmental agency in the United States that certifies that a herbal product is what it claims to be. Reputable companies producing herbal remedies bioassay the product after manufacture and list on the label that the product contains a standardized herbal extract, listing the percent of the known active ingredient(s).
As in every other aspect of medicine, hypnosis is both an art and a science. Those readers who are familiar with the nuances of hypnotic phenomenon are well acquainted with the art. This brief introduction to the field of Medical Hypnosis will focus on the history, theories, clinical applications and research investigations into the use of hypnosis as a medical intervention. When consulting the references used to prepare this review of the literature, the reader will note that medical,dental and psychological uses of hypnosis have undergone mainstream scientific testing of its effectiveness since the late 1950's.
In 1734 Franz Anton Mesmer, a Viennese physician, began the modern medical study of hypnosis through interventions designed to alter the flow of electro-magnetic fluids in the body. 29, 30 This treatment, later called "animal magnetism", was documented as instrumental in miraculous cures of individuals unresponsive to contemporary medical interventions. In 1784, an international commission, led by Benjamin Franklin, was appointed by the King of France to investigate Mesmerism's claims. Without disputing the "cures" attributed to Mesmerism, the findings elucidated the impact of an individual's imagination in the healing process and the ability of a practitioner to manipulate this imagination.31
Despite unbelievable "cures", the medical profession forced Mesmerism to remain virtually unused even after the mid 1800's, when it's application in India as the sole anesthetic during at least 300 surgeries was documented by Dr. James Esdaile, a Scottish surgeon.32, 31 Finally, in 1842, James Braid, a British surgeon, coined the term "hypnosis" equating it with sonombolistic sleep. This definition moved mesmerism away from magnetism and energy flow towards the theory of it as an induced state of consciousness.31 The professional recognition of hypnosis was achieved in the late 1950's upon the development of several medical, dental and psychological societies dedicated to the scientific study and clinical application of hypnosis.33
While academic and experimental investigations of hypnosis have revealed a wealth of data, no one has agreed upon a definition of hypnosis.34 Milton Erikson, M.D., founding father of the American Society of Clinical Hypnosis, taught that a hypnotic trance state was a natural phenomenon that correlates with changes in neuro-hormonal rhythms.35 It is on these very same states upon which marketing professionals and television evangelists depend! Basically, it is believed that hypnosis works as a tool that facilitates the suspension of critical thinking processes allowing communication to take place directly with the sub-conscious mind. Logical thinking is bypassed, facilitating the acceptance of the illogical.
Most medical hypnotic inductions (the specific interventions through which hypnotic phenomenon are stimulated), employ a structured approach to elicit specific cognitive and physiologic responses whether or not a spontaneous trance exists. The ability of a person to perform certain hypnotic skills depends on several factors. The first factor known to influence an individual's hypnotizability is expectancy. Prior experience or exposure to hypnosis and belief based on that information shapes an individual's entire responsiveness to the hypnotic intervention. It is for this reason practitioners assess what individuals are expecting from their experience and dispel misconceptions.36
The most important facet of hypnosis for medical interventions is dissociation. Individuals vary in their ability to turn on or off certain psychological or physiological processes. Through cognitive dissociation athletes can enhance their performance and cut off sensory feedback from their body.37 A closely related factor to dissociation, is the concept of absorption. While individuals who score high on absorption scales may not be able to turn off sensation, they are able to become "mesmerized" by something other than the undesired experience. 38,39
The fourth influencing factor in hypnotizability is one's response to suggestion. Once a light trance state is induced, therapeutic hypnotic suggestions are formulated and shared with the hypnotized individual. An individual's innate tendency to accept or reject suggestions influences their responsiveness. Resistance of suggestions occurs when there is an absence of the suspension of critical thinking.31 Last but not least, motivation plays a key role in achieving hypnotic states. Individuals involved in crisis situations can access deeper levels of hypnosis based on the situational motivation. Also, individuals motivated to please their care givers will perform according to the socialized role of subject to the hypnotic master.40
Most of the experimental data suggests that varying degrees and dimensions of these five hypnotic traits influences an individual's ability to "be hypnotized". Standardized scales of hypnotizability are used in experimental and clinical settings to assess an individual's ability to engage in certain tasks. Selection of appropriate hypnotic inductions depends upon hypnotizability levels.31 It is generally believed that all hypnosis is self hypnosis and an individual cannot be hypnotized against their will. However, through by-passing the conscious critical adult mind people are capable of feats that they may consciously not believe are possible.33
It is accepted that hypnosis induces a state of relaxation and well being, however, the most convincing aspect of hypnosis is being able to willfully influence physiological processes.35 Controlled experiments and clinical interventions document the ability of hypnotized individuals to control pain,31, 33, 35, 40-45 reduce physiologic arousal in preparation for and during surgery,32, 46 replace or supplement chemical anesthesia and analgesia31, 32, 47-49 and reduce bleeding, swelling, infection, post-operative complications and pain31-33, 40, 50 and reduce length of hospital stay32 (see Figure 3).
| Figure 3. Randomized / Double Blinded Clinical Trials Of
Hypnosis And Surgery (Blankenfield, 1991)32 The most significant data reflects a decreased length of hospital stay for 211 out of 316 patients (67% in three out of five studies reported). Average decreased length of stay was 1.5 days. Other trials included in Blankfield's study (18 in all) were not randomized, double blinded placebo controlled as are the ones above. However, they reflected similar or better results when integrating pre-surgical, intra-operative, and post-operative hypnosis. |
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In dentistry, hypnosis is used for psychogenic oral pain,51 overcoming fear, gagging,52 tongue thrusting, thumb sucking, flow of saliva and capillary bleeding, bruxism, cooperation with procedures and as an anesthetic in place of chemical anesthesia due to allergies. 53 In obstetrics there are many documented cases of hypnosis assisting with hyperemesis gravidarum,54 preparation for labor and delivery31,33,40,55-57 and during c-section for hypnoanesthesia.31, 33, 40, 58 Smoking cessation and habit control programs are more successful with the inclusion of hypnosis31, 33 and individuals have demonstrated measurable modulation of the autonomic, endocrine, immune and neuropeptide systems in the body while hypnotized.35
In dermatology, hypnosis has shown great success for removal of warts,59, 60 reduction of burns,61-63 reversal of allergic reactions33, 64 and has proven helpful with many other diseases of the skin.64 Psychiatric applications of hypnosis have shown effectiveness in mood disorders, eating disorders, enuresis, hypochondriasis, psychogenic impotence, premature ejaculation, insomnia, dissociative identity disorder, personality disorders, phobias, various psychosomatic disorders, stuttering, tics and vaginismus.31,33,35 The reader is encouraged to explore other resources for additional medical, surgical, dental and psychological applications of hypnosis.65
Prior to diagnosis related groups (DRG's) and other cost containing measures, the motivation to included hypnosis in mainstream medicine was not present. The cost savings in successful treatment of psychogenic, dissociative and psychosomatic conditions, all high utilizers of medical treatments, is unimaginable. Another key area for cost savings is demonstrated in decreased length of hospital stays, lowered uses of pain medications and reduced complications post-surgically.32
In response to these findings, Medicare has approved the use of medical hypnosis (CPT 90880) for treatment of phobias, psychogenic pain, conversion and dissociative disorders.66 Florida Statute (§456) on the Practice of Hypnosis, limits this therapy to licensed practitioners of the healing arts, including physicians, psychiatrists, dentists, chiropractors, podiatrists, and optometrists "within the perview of the statutes applicable to his respective profession". A patient may be referred to a "qualified practitioner" by a licensed practitioner of the healing arts, but that "qualified practitioner" must employ hypnotic techniques under the supervision, direction, prescription, and responsibility of such referring practitioner.66
There are several professional societies which regularly offer training in hypnosis that complement various medical specialties. However, experience is the best teacher and there is no better method of learning what hypnosis can help individuals achieve than trying it yourself! The authors of this paper encourage all physicians to recognize the long history of medical hypnosis and the fact of it's professional standing in the healthcare community. Encouraging patients to tap into their psycho-physiological abilities through learning self-hypnosis will complement and enhance the course of treatment physicians feel is best for their patients.
Jacksonville Medicine / January, 2000
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